Trayectorias divergentes de las desigualdades socioeconómicas absolutas y relativas en la inmunización infantil en 109 países, 1991–2023
Palabras clave:
inmunización infantil, desigualdad socioeconómica, cero dosis, índice de desigualdad de la pendiente, índice relativo de desigualdadResumen
La expansión de la inmunización infantil puede realzar la cobertura promedio sin eliminar las desigualdades socioeconómicas. Valoramos su magnitud, tendencia y persistencia en cinco indicadores y si la reducción absoluta estuvo acompañada de convergencia relativa. Estudio ecológico longitudinal con evaluaciones del WHO Health Inequality Data Repository. La base circunscribió 288,486 registros. El estudio comprendió 2,113 combinaciones país–encuesta–indicador de 109 países entre 1991 y 2023. Se valoraron el índice de concentración, el índice relativo de desigualdad (RII), el índice de desigualdad de la pendiente (SII) y el índice de Erreygers. La perplejidad se propagó mediante 500 simulaciones de Monte Carlo. Se emplearon modelos ponderados por precisión, ingreso y modelos multinivel, ajuste por región Y errores estándar agrupados por país. La perseverancia requirió un límite inferior del IC95% del SII mayor que cero en las dos encuestas recientes de los países con al menos tres ondas.
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Bergen, N., Cata-Preta, B. O., Schlotheuber, A., Santos, T. M., Danovaro-Holliday, M. C., Mengistu, T., Sodha, S. V., Hogan, D. R., Barros, A. J. D., & Hosseinpoor, A. R. (2022). Economic-related inequalities in zero-dose children: A study of non-receipt of diphtheria–tetanus–pertussis immunization using household health survey data from 89 low- and middle-income countries. Vaccines, 10(4), Article 633. https://doi.org/10.3390/vaccines10040633
Bergen, N., Schlotheuber, A., Kirkby, K., Arroyave, L., Danovaro-Holliday, M. C., Barros, A. J. D., & Hosseinpoor, A. R. (2026). State of inequality in childhood immunization: Monitoring progress across low- and middle-income countries over the past decade. Vaccines, 14(4), Article 296. https://doi.org/10.3390/vaccines14040296
Bobo, F. T., Asante, A., Woldie, M., Dawson, A., & Hayen, A. (2022). Child vaccination in sub-Saharan Africa: Increasing coverage addresses inequalities. Vaccine, 40(1), 141–150. https://doi.org/10.1016/j.vaccine.2021.11.005
Causey, K., Fullman, N., Sorensen, R. J. D., Galles, N. C., Zheng, P., Aravkin, A., Danovaro-Holliday, M. C., Martinez-Piedra, R., Sodha, S. V., Velandia-González, M. P., Gacic-Dobo, M., Castro, E., He, J., Schipp, M., Deen, A., Hay, S. I., Lim, S. S., & Mosser, J. F. (2021). Estimating global and regional disruptions to routine childhood vaccine coverage during the COVID-19 pandemic in 2020: A modelling study. The Lancet, 398(10299), 522–534. https://doi.org/10.1016/S0140-6736(21)01337-4
Dimitrova, A., Carrasco-Escobar, G., Richardson, R., & Benmarhnia, T. (2023). Essential childhood immunization in 43 low- and middle-income countries: Analysis of spatial trends and socioeconomic inequalities in vaccine coverage. PLOS Medicine, 20(1), Article e1004166. https://doi.org/10.1371/journal.pmed.1004166
Evans, B., Keiser, O., Kaiser, L., & Jombart, T. (2023). Analysis of global routine immunisation coverage shows disruption and stagnation during the first two-years of the COVID-19 pandemic with tentative recovery in 2022. Vaccine: X, 15, Article 100383. https://doi.org/10.1016/j.jvacx.2023.100383
Evans, B., Kaiser, L., Keiser, O., & Jombart, T. (2025). Routine immunisation coverage shows signs of recovery at global level postpandemic, but important declines persist in about 20% of countries. Vaccines, 13(4), Article 388. https://doi.org/10.3390/vaccines13040388
Flatt, A., Vivancos, R., French, N., Quinn, S., Ashton, M., Decraene, V., Hungerford, D., & Taylor-Robinson, D. (2024). Inequalities in uptake of childhood vaccination in England, 2019–23: Longitudinal study. BMJ, 387, Article e079550. https://doi.org/10.1136/bmj-2024-079550
Fullman, N., Correa, G. C., Ikilezi, G., Phillips, D. E., & Reynolds, H. W. (2023). Assessing potential exemplars in reducing zero-dose children: A novel approach for identifying positive outliers in decreasing national levels and geographic inequalities in unvaccinated children. Vaccines, 11(3), Article 647. https://doi.org/10.3390/vaccines11030647
GBD 2020, Release 1, Vaccine Coverage Collaborators. (2021). Measuring routine childhood vaccination coverage in 204 countries and territories, 1980–2019: A systematic analysis for the Global Burden of Disease Study 2020, Release 1. The Lancet, 398(10299), 503–521. https://doi.org/10.1016/S0140-6736(21)00984-3
Hogan, D., & Gupta, A. (2023). Why reaching zero-dose children holds the key to achieving the Sustainable Development Goals. Vaccines, 11(4), 781. https://doi.org/10.3390/vaccines11040781
Johns, N. E., Santos, T. M., Arroyave, L., Cata-Preta, B. O., Heidari, S., Kirkby, K., Munro, J., Schlotheuber, A., Wendt, A., O’Brien, K., Gupta, A., Barros, A. J. D., & Hosseinpoor, A. R. (2022). Gender-related inequality in childhood immunization coverage: A cross-sectional analysis of DTP3 coverage and zero-dose DTP prevalence in 52 countries using the SWPER Global Index. Vaccines, 10(7), 988. https://doi.org/10.3390/vaccines10070988
Johri, M., Rajpal, S., & Subramanian, S. V. (2021). Progress in reaching unvaccinated (zero-dose) children in India, 1992–2016: A multilevel, geospatial analysis of repeated cross-sectional surveys. The Lancet Global Health, 9(12), e1697–e1706. https://doi.org/10.1016/S2214-109X(21)00349-1
Kirkby, K., Antiporta, D. A., Schlotheuber, A., Menéndez, P., Danovaro-Holliday, M. C., & Hosseinpoor, A. R. (2024). Quantifying inequalities in childhood immunization using summary measures of health inequality: An application of WHO Stata and R ‘healthequal’ packages. Vaccines, 12(12), Article 1324. https://doi.org/10.3390/vaccines12121324
Kirkby, K., Bergen, N., Schlotheuber, A., Sodha, S. V., Danovaro-Holliday, M. C., & Hosseinpoor, A. R. (2021). Subnational inequalities in diphtheria–tetanus–pertussis immunization in 24 countries in the African Region. Bulletin of the World Health Organization, 99(9), 627–639. https://doi.org/10.2471/BLT.20.279232
Lyons, C., Nambiar, D., Johns, N. E., Allorant, A., Bergen, N., & Hosseinpoor, A. R. (2024). Inequality in childhood immunization coverage: A scoping review of data sources, analyses, and reporting methods. Vaccines, 12(8), 850. https://doi.org/10.3390/vaccines12080850
Rajpal, S., Kumar, A., Johri, M., Kim, R., & Subramanian, S. V. (2023). Patterns in the prevalence of unvaccinated children across 36 states and union territories in India, 1993–2021. JAMA Network Open, 6(2), e2254919. https://doi.org/10.1001/jamanetworkopen.2022.54919
Shet, A., Carr, K., Danovaro-Holliday, M. C., Sodha, S. V., Prosperi, C., Wunderlich, J., Wonodi, C., Reynolds, H. W., Mirza, I., Gacic-Dobo, M., O’Brien, K. L., & Lindstrand, A. (2022). Impact of the SARS-CoV-2 pandemic on routine immunisation services: Evidence of disruption and recovery from 170 countries and territories. The Lancet Global Health, 10(2), e186–e194. https://doi.org/10.1016/S2214-109X(21)00512-X
Silva, L. A. N., Costa, F. S., Cata-Preta, B. O., Huicho, L., Lanata, C. F., Mendoza Araujo, M. A., Ochoa, T. J., Mengistu, T., Hogan, D., Barros, A. J. D., & Victora, C. G. (2025). The impact COVID-19 pandemic on coverage and inequalities in childhood immunization in Peru. International Journal for Equity in Health, 24, Article 138. https://doi.org/10.1186/s12939-025-02505-3
Spencer, N., Markham, W., Johnson, S., Arpin, E., Nathawad, R., Gunnlaugsson, G., Homaira, N., Mesa Rubio, M. L., & Jaime Trujillo, C. (2022). The impact of COVID-19 pandemic on inequity in routine childhood vaccination coverage: A systematic review. Vaccines, 10(7), 1013. https://doi.org/10.3390/vaccines10071013
Williams, S. V., Akande, T., & Abbas, K. (2024). Systematic review of social determinants of childhood immunisation in low- and middle-income countries and equity impact analysis of childhood vaccination coverage in Nigeria. PLOS ONE, 19(3), e0297326. https://doi.org/10.1371/journal.pone.0297326
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Derechos de autor 2026 Nader Brian Flores Incahuanaco, Yeny Hurtado Flores, Percy Flores Laime, Roberto Torres Rua, Hugo Hernan Flores Laime

Esta obra está bajo una licencia internacional Creative Commons Atribución 4.0.













